width-wise you lose around 1.5 or 2 inches, i forget exactly how much but you also close the front to back wheel well line. it shrinks maybe 1 inch in the front and 1 inch in the back.
the 4x fenders flare up and out... the 2wd fenders have no flare and have a lower top line on the bottom of the fender. depending on your lift and tire combo you may have to trim here and there....