CRSHROX, its all going to depend on what angle your driveline is actually at.. thats going to determine whether or not you'll have to "clearance" them... remember the more you clearance the weaker they'll be so prevent that at all costs.
I've found a great way to help driverline binding for people who run an extreme angle. Ever see those mowers that mow on side hills and have the "flap" blades that move up and down? That's a driveline under there and the CV's for those can take an extreme angle without rubbage but they're a bit pricey.. ALSO they make a pretty beefy set for offroad applications.