Yea until you find that they've manafested themselves in the registry files and your pulling your hair out deleteing a million fraud/corrupt files.. lol
LOL.. this is very true. I have spent well past 3 hours manually scraping the registry clean at work, only to finally have to reinstall. Sometimes they are like mushrooms, as soon as you pluck them they release a bunch of spores that infect new areas. that has usually been with browser hijackers though. most trojans are easy.
I guess i don't like being defeated sometimes.