I have a really old Haynes Manual with some cam information and it has the same difference for 20r/22r vs. 22re. The cam I have in. my 22r now is the stock EFI profile because that is all that is available as a stock replacement these days.
I measured an original early 22r cam vs. a 22re cam and it did mic out a little bigger on the intake side if that means anything. Biggest difference if this is all true is the difference in the duration intake/exhaust. That has to do something big.