screw it. Put in a high horspower 7MGTE
Seriously tho, you need to decide what you really want. A slightly massaged 22RE has plenty of power for 35-37"tires in my opinion. If you want to cruise at 80 all day on the freeway, then maybe not, but thats why I bought a tow rig...
Is this truck your DD? Where do you live (flat country, hilly country, somwhere in-between?) What is your budget? How is your truck setup?