I know a couple people who had 42"s on their yota axles. With no real problems, but they arnt the type of drivers who hit rev limiter, while the truck is bouncing trying to make it up an obstacle.
And many many more who have 40"s. I ran 39.5" iroks in the snow and smashed on it pretty decently never had an issue.
You have a good set of on road/off road tires that should give you plenty of miles. Dont mistakenly think the iroks will be the same. My $0.02