I have not even driven the 4Runner since I put WaterWetter in the radiator, but I was just reading the Technical White Paper on the website and noticed the following:
"COOLANT EFFECTS ON PERFORMANCE
Under moderate load conditions, each percent glycol
raises cylinder head temperatures by 1°F. 50% glycol
raises head temperatures by 45°F. This increase in
temperature will raise the octane required for trace
knock levels by typically 3.5 octane numbers. A car
equipped with a knock sensor will retard the timing to
compensate for the increase in octane requirement
by approximately 5°, which will reduce the maximum
brake torque by about 2.1%. Racing vehicles not
equipped with knock sensors can advance timing for
increased torque."
It might actually make a difference. In any case, it was interesting info.