Main work would be in the head of course. Keeping the intake runners long will help. Having the valves as big as I want will work better with a 20R or early 22R, the combustion chambers in the later 22R help with swirl, but act as a dam to intake flow. I've decided to use the 20R I have, 47.5mm intake and 37.5mm exhaust, just do a little more work to the ports and work the 22RE lower mani to match(another story altogether). The work there will increase flow quite a bit without losing the needed charge velocity. A few little tricks to enhance swirl will help with keeping the fuel suspended in the intake charge and a more complete burn. Since I am keeping the valves I already have in the head anything more than a .470 lift will be overkill, just need a good aggressive opening ramp cam. Wonder if I can get a grind like I had in one of my VWs, hmmm.
As for a tri-Y header? I've had better low end numbers in the past with them, the shorty headers do pretty well, but the pulse tuning on the tri-Y seems to evacuate better for low end. My experience and opinion.