I love my 22r and I don't want a 3RZ in my 4Runner anymore, but I will concede you will never, ever get the power, drivability and economy of the 3RZ with a 22RE, even on a pimp's budget.
I agree, but I was only really after a few more lbs of torque and a couple more HPs for passing.
As I said, if I wanted a reasonably low cost investment, serious power, with high reliability, availability of parts, fuel economy, and me being able to work on it... I'd swap in a Chevy 4.3 L Vortec V-6.
Gnarls.