most guys dont for a couple resons, first is the drop like you mentioned, its pass drop, so you need to flip the axle or swap to a diff t-case, the second is that most toy axles are a little narrow, but that can be fixed with spacers or widening kits.
I was going to go that route on my runner, and I would have, If I didnt get a great deal on some full widths.
I say do it and it will be bad ass......