I guess that you are talking about an FD motor available in RX-7's from 93-95, that would be twin turbo and 225hp. You are talking about dealing with wiring issues like no other, and a great amount of $$. I have owned several RX-7's and they are alright, but I would not think about swapping them into anything heavier than a RX-7.
If you are not talking about an FD, then your HP numbers are way off. Porting a rotary will free up power at the top, but take it away at the bottom.