getting it adjusted the right way is going to be critical.
And a pregnant dog! I've run a weber on my 4by for a few years and would say steer clear! Glen's right about the stock 22r carb, the flow is about 1cfm lower on a stock carb. If you could find a good clean 22r carb then you could buy the LC engineering adapter from lilbuddy(pm him or find his ad in the for sale section) to run it on a 20r manifold.