Monarch made a 4-1 back in the 80s, that's what Marlin runs and it kicks ass.
Downey makes a 4-1 and so does LC Engineering, both are great headers and I will probabely run one some day.
North West makes a 4-2-1 -- known as a Tri-Y -- but they are difficult to order from and I have never used one.
I am sure some other companiese like Hooker might make headers for 22Rs but I bet it is just something the make to fill their online catalog with. Stick to the Yota companies, such as Downey and LC and your do great :up:
FYI, 4-2-1 offer good mid range power, while 4-1 offer good mid-high power. But focus more in the actual size of the primaries (the ID size that will be bolting right up to your head). Smaller sizes will allow for better bottom end and torque while larger sizes will be the opposite.
Regards,
BigMike